This article informs the relationship between Capsaicin and its effects on the gastrointenstinal system.

Please see the link here: LINK

This study evaluates the effect of capsaicin on heartburn, dyspepsia, and gastric acidity to test the hypothesis that capsaicin induces heartburn and exacerbates symptoms by sensitizing the oesophagus

Link: HERE

This study is aimed at determining whether capsaicin infusion could influence heartburn perception and other effects.

Link: HERE

This study showed certain proteins help reduce the burning sensation from capsaicin. A 5% protein solution was much better than water at easing the burn.

Link: HERE

High doses of capsaicin (CAP) caused noticeable inflammation and damage to the intestines in mice. This inflammation was linked to higher levels of certain neuropeptides and short-chain fatty acids, indicating that changes in gut bacteria are likely involved.

Link: HERE